Storage and handling of biological samples without refrigeration

Edit Hook

Biomatrica®’s core technology stabilizes biological materials at room temperature – preserving sample integrity and increasing reproducibility and reliability. Their technology platform and continuous innovation enables labs to perform their research with increased confidence and efficiency.

Key Differentiators

Biomatrica® developed SampleMatrix® to stabilize and protect biological materials at room temperature without degradation. The SampleMatrix technology was designed by combining extremophile biology, that enables long-term survival of organisms in extremely dry environments, with synthetic chemistry. By exploiting these unique characteristics, Biomatrica products enable researchers to stabilize biological samples for long periods of time with complete and rapid sample recovery. Watch Video a video from Biomatrica below.

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Biomimicry Story

The founders of Biomatrica®, Rolf Muller and Judy Muller-Cohn, got their inspiration when visiting a toy store. They noticed sea monkeys, which are really brine shrimp that are in a dried state but come back to life when rehydrated. After research into the strategy used by brine shrimp, resurrection fern (spikemoss family), tardigrades, and other organisms, they created a thermostable, dissolvable glass that packages every single molecule in a sample. Rather than using the molecule trehalose, they created a molecule that performs the same function.

Challenges Solved

Presently, biological materials such as nucleic acids, proteins, cells, and membranes, are maintained and transported in cold environments (4ºC, -20ºC, -80ºC, and liquid nitrogen) to preserve sample integrity. Multiple freeze-thaw cycles or prolonged exposure to increased temperatures degrade precious and labile biological materials. Sustaining cold environments requires constant energy supplies and resources that are not always readily available or reliable. Consequently, transporting and storing biological samples oftentimes involves enormous expense and complicated logistics. Despite elaborate precautions taken to maintain sample integrity, it has been difficult to control all environmental variables.Currently, the cost of refrigeration in labs worldwide comes to $30 billion. Imagine the energy savings if samples could be stabilized at room temperature.

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