The ability of Pyrolobus fumarii archaea to survive extreme heat may be related to the accumulation of charged organic solutes.

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"The archaeon Pyrolobus fumarii, one of the most extreme members of hyperthermophiles known thus far, is able to grow at temperatures up to 113°C. Over a decade after the description of this organism our knowledge about the structures and strategies underlying its remarkable thermal resistance remains incipient. The accumulation of a restricted number of charged organic solutes is a common response to heat stress in hyperthermophilic organisms and accordingly their role in thermoprotection has been often postulated." (Gonçalves et al. 2008:383)

Journal article
Di- myo -inositol phosphate and novel UDP-sugars accumulate in the extreme hyperthermophile Pyrolobus fumarii

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Journal article
Pyrolobus fumarii , gen. and sp. nov., represents a novel group of archaea, extending the upper temperature limit for life to 113�CExtremophilesAugust 25, 2002
Doris Hafenbradl, Holger W. Jannasch, Karl O. Stetter, Elisabeth Bl�chl, Reinhard Rachel, Siegfried Burggraf

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