RNAstāble from Biomatrica uses synthetic chemistry to stabilize biological samples at room temperature.


  • Reduced cost
  • Eco-friendly
  • Saves space
  • Eliminates sample refrigeration


  • Biological samples

UN Sustainable Development Goals Addressed

  • Goal 3: Good Health & Wellbeing

  • Goal 12: Responsible Production & Consumption

The Challenge

Biological samples are often stored in a freezer, which makes them vulnerable to equipment malfunction and oftentimes leads to sample degradation over time. In addition, shipping of frozen samples requires dry ice, which is costly and uses excessive materials.

Innovation Details

RNAstāble™ mimics the trehalose to stabilize and protect biological materials at room temperature. It is a thermostable, dissolvable glass that packages every single molecule in a sample.

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Biological Model

Anhydrobiosis is the process by which organisms such as brine shrimp and tardigrades become almost completely dehydrated, losing up to 95% of their free and stored water and entering a state of suspended animation. They can survive in this state for several decades. To enter this state, the organism creates different proteins and sugars that help protect its cells. One sugar, trehalose, is known to help organisms survive dessication. Although it is not known exactly how trehalose works, it is hypothesized that this protein helps with water absorption and prevents ice crystal formation, which can damage cells. Once the organism takes up water again from its surroundings it can re-activate its cells and come back to life.