µLot Platform Technology from Swedish Biomimetics 3000 uses discrete reaction units that help improve peptide manufacturing.
Benefits
- Reduced cost
- Reduced waste
- Reduced energy use
Applications
- Pharmaceuticals
- Drug discovery
UN Sustainable Development Goals Addressed
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Goal 3: Good Health & Wellbeing
The Challenge
Two families of pharmaceuticals, peptides and oligonucleotides, have the potential to treat a very wide range of diseases. However, they are very expensive to produce and are often made using batch manufacturing, which produces unnecessary waste.
Innovation Details
µLot® Platform Technology uses a reaction system of multiple reaction and purification stages to create a chemical assembly line, similar to how ribosomes transcribe RNA to form proteins. An elongated cord or ribbon containing reactive chemical groups is moved continuously between the reaction and purification stages. A product is then slowly created, cleaved and then collected using acid. This process requires less space and significantly reduces waste and energy use.
Biological Model
Ribosomes are found in every living organism. They continuously move along RNA to transcribe it into proteins for use by cells.
