Piscidin-2 opening channels in cell membrane of a fungal species. Artist: Emily Harrington. Copyright: All rights reserved. See gallery for details.
"Piscidins are 22-residue peptides first purified from skin and gills of hybrid striped bass...All piscidins show broad-spectrum antimicrobial activity...Recently, piscidin-2 has been found to cause cell membrane damage to three fungal strains known to cause infections in humans." (Smith et al. 2010:1219)
"[O]rganisms express a very wide range of compounds including not only conventional, (i.e., 'dedicated') antimicrobial peptides within the immune system but also a large array of proteins, protein fragments, lipoproteins, glycoproteins or other factors that have, or are derived from, compounds with other primary biological functions. The sheer number of different types expressed even within a single species is quite remarkable." (Smith et al. 2010:1240)