The Wood–Ljungdahl pathway (or reductive acetyl–CoA pathway) is a series of biochemical reactions used by these anaerobic bacteria to synthesize acetyl-CoA. This pathway allows the organism to use hydrogen as an electron donor and carbon dioxide as an electron acceptor. Unlike other energy production pathways (e.g., the Calvin cycle) this process is not cyclic. For details on how this process works, please see the image gallery.
Depiction of how the Wood–Ljungdahl pathway produces acetyl-CoA. Artist: Yikrazuul. See gallery for molecular structure of acetyl-CoA.